Microbiology Quiz #8

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Last updated: May 5, 2024

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First submitted	May 5, 2024
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Average score	13.0%
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Hint	Answer
Tests strips which contain a gradient of an antibiotic, convenient for use with anaerobic pathogens	ETest
Lowest concentration of drug that kills pathogen	Minimal lethal concentration
What does penicillin prevent bacteria from completing causing lysis?	Cell wall
Antimicrobial agent which kills microbes	Cidal
Who accidentally discovered penicillin in 1928?	Alexander Fleming
What do β-lactams and vancomycin target?	Cell Wall
Drugs effective against a limited number of different pathogens	Narrow Spectrum
Test where disks impregnated with specific drugs are placed on agar plates inoculated with test microbe	Disk Diffusion
Ratio of toxic dose to therapeutic dose	Therapeutic index
Who originally discovered penicillin in 1896?	Ernest Duchesne
Drug level at which drug becomes too toxic for patient (i.e., produces side effects)	Toxic dose
Test which involves inoculating media containing different concentrations of drug	Dilution Susceptibility

Hint	Answer
Standardized method for disk diffusion test	Kirby-Bauer Method
Ability of drug to kill or inhibit pathogen while damaging host as little as possible	Selective toxicity
Antimicrobial agent which limits growth of microbes	Static
What do fluoroquinolones and rifamycin's target?	DNA/RNA synthesis
Drug level required for clinical treatment	Therapeutic dose
Drugs effective against a wider range of different pathogens	Broad spectrum
Which inhibitor mimics peptide bond that is normally attacked by the enzyme?	Protease
What do linezolid, tetracyclines, macrolides, and aminoglycosides target?	Protein synthesis
Lowest concentration of drug that inhibits growth of pathogen	Minimal inhibitory concentration
What do trimethoprim and sulphonamides target?	Folate synthesis
What does daptomycin target?	Cell membrane

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