Year
|
Location
|
Symptoms
|
Disease
|
2015-16
|
Brazil
|
Birth defect microcephaly
|
Zika
|
1952
|
United States
|
Paralysis
|
Polio
|
1340-1400
|
Europe
|
Swollen lymph nodes, sometimes as large as chicken eggs, in the groin, armpit, or neck
|
Bubonic Plague
|
1854
|
United Kingdom
|
Diarrhea, dehydration
|
Cholera
|
2014
|
Western Africa
|
Internal bleeding, vomiting or coughing up blood
|
Ebola
|
541 AD
|
Eastern Roman Empire
|
Swollen lymph nodes, necrosis of the hands
|
Plague of Justinian
|
2009
|
Mexico, United States
|
Fever, cough, sore throat, chills, body aches
|
Swine Flu
|
1793
|
United States (Philadelphia)
|
Fever, headache, nausea, vomiting
|
Yellow Fever
|
165-180 AD
|
Middle East, Roman Empire
|
Fever, diarrhea, pharyngitis, skin eruption
|
Antonine Plague
|
1633-34
|
United States (New England)
|
Virus-filled sores on the skin
|
Smallpox
|
1918
|
United States
|
Fever, chills, muscle aches, cough, etc.
|
Spanish Flu
|
1600s
|
Europe
|
Fever, cough, headache, abdominal pain, etc.
|
Typhus
|
Tens of thousands of years ago-today
|
Sub-Saharan Africa (Today)
|
Chills, fever, sweating
|
Malaria
|
1981-present
|
Worldwide
|
Immune deficiency
|
AIDS
|
17th-19th century
|
Europe
|
Cough (sometimes with blood), weight loss, night sweats, fever
|
Tuberculosis
|
|